Progestin treatments may decrease fertility

Polycystic Ovarian Syndrome (PCOS) is a hormonal condition that affects many women.  It is considered one of the most common female endocrine disorders and leading causes of female infertility.

The condition is characterized by the growth of cysts on a woman’s ovaries, which leads to a disruption in hormone balance.  It’s often associated with excessive body hair, menstrual irregularities, weight gain, and hair loss.

Many treatments for the disease include taking Progestin, a synthetic form of the hormone progesterone, which helps the lining of the uterus thicken.

Additionally, Progestin use is often prescribed prior to ovulation in women undergoing fertility treatments.

However, recent data suggests that Progestin use may be correlated with decreased fertility.

In a study testing the effects of Progestin on fertility, taking Progestin prior to ovulation was found to decrease pregnancy rates in women undergoing fertility treatments.  Only 5% of women taking Progestin gave birth, while 20% of women omitting Progestin successfully conceived.

Therefore, women undergoing fertility treatments should be aware that Progestin treatments prior to ovulation may decrease their chances at conception.

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